The next industrial revolution will fundamentally change the way we make things, and where. The transformation to digital fabrication, based on binary or genetic code, will impact everything from settlement patterns to labor, education, transportation, public health, the environment, and warfare. Government needs to create policy frameworks that support the transition to a new manufacturing paradigm and we also need to have a public conversation about what this world should look like and what policies are needed to make sure that both society and the planet will benefit.