Latin America and the Caribbean face multiple risks from a changing climate, from sea level rise to glacial melt to extreme weather and disease. Recent population trends—particularly population growth and urbanization—will continue to be an important factor in influencing the region’s vulnerability and adaptive capacity. This policy brief shares highlights, key findings and lessons from a series of seminars on climate change adaptation organized by the Wilson Center and U.S. Agency for International Development missions across Latin America and the Caribbean. Adaptive capacity in the region is growing, and the process of consultation drew attention to projects that demonstrate innovative approaches in participatory planning, private sector engagement, payment for ecosystem services, urban planning, and mainstreaming climate change into broader development objectives. As the impacts of climate change become more severe, however, the need for effective climate change adaptation action and resources will grow. Creating shared learning networks through convening climate change practitioners and policymakers will be an important part of the strengthening the region’s capacity to adapt.